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. 2018 Mar 27;15(3):e1002543. doi: 10.1371/journal.pmed.1002543

Fig 3. Cancer HRs of frailty scores (n = 4,792): Continuous and cutoff analysis.

Fig 3

(A) Left panel: continuous analysis; (B) right panel: categorical analysis. Models were fitted using age as timescale, with time 0 = age at entry of study and time 1 = age at event or censoring date. Model 1 in blue: adjusted by sex. Model 2 in red: Model 1 + smoking status, alcohol, and alcohol consumption. Model 3 in green: Model 2 + physical activity, BMI, diabetes, hypertension, cardiovascular, anaemia, COPD, arthritis, neuropsychiatric problems, depression, cognition, and self-rated health and quality of life. HRs were at 2.5 years (median follow-up for cancer events). BDE, Beaver Dam Eye Study Index; BFI, Brief Frailty Index; BMI, body mass index; CGA, Comprehensive Geriatric Assessment; CGAST, Comprehensive Geriatric Assessment Screening Tests; COPD, chronic obstructive pulmonary disease; CSBA, Conselice Study of Brain Aging Score; CVD, cardiovascular disease; EFIP, Evaluative Frailty Index for Physical Activity; EFS, Edmonton Frail Scale; FI40, 40-item Frailty Index; FI70, 70-item Frailty Index (SHARE); FIBLSA, Frailty Index Beijing Longitudinal Study of Ageing; FiND, Frail Non-Disabled Questionnaire; FS, Frail Scale; FSS, Frailty Staging System; G8, G-8 Geriatric Screening Tool; GFI, Groningen Frailty Indicator; HR, hazard ratio; HRCA, Hebrew Rehabilitation Center for Aged Vulnerability Index; HSF, Health Status Form; IFQ, Inter-Frail Questionnaire; MFS, Modified Frailty Score; MPHF, Modified Phenotype of Frailty; NLTCS, Long Term Care Survey Frailty Index; PFI, Physical Frailty Index; PHF, Phenotype of Frailty; SDFI, Static/Dynamic Frailty Index; SHCFS, Canadian Study of Health and Aging Clinical Frailty Scale; SI, Screening Instrument; SOF, Study of Osteoporotic Fractures; SPPB, Short Physical Performance Battery; SPQ, Sherbrooke Postal Questionnaire; TFI, Tilburg Frailty Indicator; VES13, Vulnerable Elders Survey; WHRH, WHOAFC and self-reported health; ZED1, ZutPhen Elderly Study (Physical Activity and Low Energy); ZED2, ZutPhen Elderly Study (Physical Activity and Weight Loss); ZED3, ZutPhen Elderly Study (Physical Activity and Low BMI).