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. 2018 Mar 27;13(3):e0193818. doi: 10.1371/journal.pone.0193818

Fig 1. The potential for high-precision targeting by pAgos.

Fig 1

A. Targeting of CRISPR/Cas9 is limited by the requirement of a PAM site (green boxes). B. NgAgo or TtAgo might allow the precise targeting of features, such as transcription factor binding sites (black boxes). gRNA/gDNA, red lines.