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. 2018 Mar 27;13(3):e0194778. doi: 10.1371/journal.pone.0194778

Fig 10. Microscopic images of spiral ganglion cells (SGCs) after two days of cultivation in different media composition.

Fig 10

The cells were cultivated in presence of the supernatants from the release experiments of BDNF-loaded amino-modified NPSNPs (NPSNP-NH2-BDNF) or of BDNF-free amino-modified NPSNPs (NPSNP-NH2). For comparison, SGCs were also cultivated in serum-free SGC medium (medium) and in serum-free medium supplemented with BDNF (50 ng mL-1 BDNF) as well as in a 1:1 serum-free medium/PBS (0.1% BSA) solution.