Table 3.

The approximate degree of neocortical pathological findings in the six patients with V180I gCJD.

	Spongiform change	Gliosis	Neuropil rarefaction	Neuronal loss
Patient 1	Severe	Moderate	Mild	Mild
Patient 2	Severe	Moderate	Mild	Mild
Patient 3	Severe	Moderate	Mild	Moderate
Patient 4	Severe	Moderate	Mild	Moderate
Patient 5	Moderate	Severe	Moderate	Severe
Patient 6	Moderate	Severe	Severe	Severe

gCJD, genetic Creutzfeldt–Jakob disease.