Table 2.

Overall efficacy of topically administered, according to any otolaryngological condition.

Topic	Overall efficacy
RAOM with or without OME	Moderately effective in prevent AOM episodes
Nasopharyngeal inflammation	Effective
Chronic rhinosinusitis	Moderately effective
CRSwNP	Moderately effective with concomitant ICS
Allergic and non-allergic rhinitis	Moderately effective with concomitant ICS
Nasal and nasosinusal surgery	Effective

RAOM: recurrent acute otitis media; OME: otitis media with effusion; AOM: acute otitis media; CRSwNP: chronic rhinosinusitis with nasal polyps; ICS: intranasal corticoid steroid.