Table 1. Clinical characteristics of patients with ERONs.
Case no. | Histology | Age (years) | FIGO Stage | Residual tumor | Recurrence | ARID1A | p53 | POLE | PTEN | PIK3CA | KRAS | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | E | 58 | IIIC | N | Y | M | WT | M | WT | WT | NA | |
2 | E | 57 | IIIC | Y | Y | M | WT | WT | WT | WT | NA | |
3 | E | 72 | IIIC | N | Y | M | M | M | M | WT | WT | |
4 | E | 60 | IV | Y | Y | M | M | M | NA | WT | WT | |
5 | E | 80 | IA | N | Y | WT | WT | WT | NA | WT | WT | |
6 | E | 59 | IC | N | N | M | WT | WT | M | M | WT | |
7 | E | 58 | IA | N | N | M | WT | WT | M | M | WT | |
8 | E | 61 | IIC | N | N | M | WT | M | M | WT | NA | |
9 | E | 50 | IC | N | N | M | M | WT | M | WT | M | |
10 | E | 47 | IC | N | N | M | WT | M | WT | WT | NA | |
11 | E | 77 | IC | N | N | M | M | M | M | WT | W | |
12 | E | 58 | IC | N | N | M | WT | WT | M | WT | NA | |
13 | E | 76 | IC | N | N | M | M | WT | NA | WT | NA | |
14 | C | 56 | IV | Y | Y | M | NA | M | WT | NA | NA | |
15 | C | 63 | IC | N | Y | M | WT | WT | M | WT | NA | |
16 | C | 55 | IIIC | Y | Y | M | M | M | M | M | WT | |
17 | C | 50 | IC | N | N | NA | NA | WT | WT | NA | NA | |
18 | C | 62 | IC | N | Y | M | WT | M | M | WT | NA | |
19 | C | 61 | IV | Y | Y | M | M | WT | M | WT | WT | |
20 | C | 50 | IC | N | N | NA | NA | WT | WT | NA | NA | |
21 | C | 71 | IC | N | N | M | WT | WT | M | WT | WT | |
22 | C | 55 | IC | N | Y | M | WT | WT | M | WT | NA | |
Mutation frequency % | 95 | 36.8 | 40.9 | 68.4 | 15.8 | 11.1 | ||||||
Previous Reports % | E C |
30(15) (16) 46-57(15)(16) |
9(20)(21) 25(20)(21) |
20(18) 8(18) |
8(7)(9) | 20(22) (23) 33-46(22 )(23) |
10(24)(25) |
NA: Not available.
WT: Wild type.
M: Mutation.
E: endometroid carcinoma.
C: clear cell carcinoma.