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. 2017 Dec 7;9(19):14803–14814. doi: 10.18632/oncotarget.22976

Figure 4. PC cell–derived IL-18 promoted immune tolerance in vivo.

Figure 4

The wild C57BL/6J mice were injected intraperitoneally with the murine pancreatic cancer cell lines Panc02 or LTPA. (A) IL-18 levels in the plasma of C57 mice were analyzed by ELISA. (B and C) The graphs show the Breg levels in PBMCs and celiac lymph nodes. (D and E) The graphs show the frequency of the main immune cell subpopulations in PBMC and celiac lymph nodes. (ns = P > .05 and no significant difference; *P < .05; **P < .01; ***P < .001.).