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. 2018 Feb 20;9(19):14993–15000. doi: 10.18632/oncotarget.24538

Table 1. Table representing the principal biological characteristics of patients used for the xenograft model.

MDS Percentage of medullary blasts at diagnostis Karyotype Molecular biology
patient 1 RAEB-2 14 46,XY,del(5)(q13q34)[11]/46,sl,add(18)(q21)[9] TP53 (G245D), SF3B1(R625H), RUNX1 (R201Q) and KIT (D816V)
patient 2 RAEB-1 4 44-45,XY,add(3)(p12),-7,add(17)(p12),mar,min [2]/46,XY [18] TP53 (G245D)
patient 3 RAEB-1 6 45,X,-Y,del(11)(q21q25)[1]/45,sl,ins(4;3)(q2?6;q28q24)[2]/90,idemx2 [1]/45,sdl1,dic(11;?)(q13;?)[12]/45,sl,t(6;12)(q25;q12),add(11)(q13)[4]/46,XY [2].ish ins(4;3)(EVI1+) TET2 (R1216X)
Patient 4 RARS 1,5 46,XX [20] SF3B1 (K666R)

RAEB: Refractory anemia with excess of blast; RARS: Refractory anemia with ring sideroblasts.