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. 2018 Feb 27;9(19):15047–15060. doi: 10.18632/oncotarget.24587

Figure 2. PPE supplementation ameliorates glucose intolerance and insulin sensitivity in CL diet-fed mice.

Figure 2

(A) Glucose tolerance test (GTT; 2 g/kg body weight) after 14 weeks (n = 6–8/group). Area under the curve calculations. (B, C). Mice on the indicated diet for 15 weeks were injected in the tail vein with saline (n = 3/group) or insulin (n = 4/group, 5 U/kg body weight), and killed 7 min after the injection. Total liver and quadriceps muscle lysates were immunoblotted for p-IRβ, IRβ, p-Akt, and Akt, quantitated, and presented as means ± SEM. *P < 0.05, **P < 0.01 vs. NC diet-fed mice. #P < 0.05, ##P < 0.01, vs. CL diet-fed mice.