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. 2018 Feb 27;9(19):15047–15060. doi: 10.18632/oncotarget.24587

Figure 3. PPE attenuates hepatic inflammation in nonalcoholic steatohepatitis (NASH) mice.

Figure 3

(A) mRNA expression of chemokine (C-C motif) ligand 2 (Ccl2), Ccl2 receptor (Ccr2), interleukin (Il)-1β, and tumor necrosis factor (Tnf)-α in the liver. (B). Immunoblot of p-Jun N-terminal kinase (p-JNK), p-extracellular signal-regulated kinase (p-ERK), phosphorylated nuclear kappa beta (p-NF-κB), p-eIF2α, GRP78, and CHOP in the liver. (C) Quantification of p-JNK, p-ERK, p-NF-κB, p-eIF2α, GRP78, and CHOP in the liver. n = 6–8. *P < 0.05, **P < 0.01 vs. NC diet-fed mice. #P < 0.05, ##P < 0.01, vs. CL diet-fed mice.