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(A) Schematic diagram of the Leishmania life cycle. (B) Role of dendritic cells and macrophages in leishmaniasis outcome. Abbreviations: IFN-γ, interferon-gamma; IL, interleukin; iNOS, inducible nitric oxide synthase; TGF-β, transforming growth factor beta; TH1 and TH2, T helper cell type 1 and 2, respectively; Treg, T regulatory cell.
