Table 3.
Risk factors for overall mortality and NRM in cHL patients
Overall mortality | NRM | ||||
---|---|---|---|---|---|
N | RR (95% CI) | P-value | RR (95% CI) | P-value | |
Age at transplant, years | <.001 | <.001 | |||
15–39 | 606 | 1.00 | 1.00 | ||
40–54 | 169 | 1.31 (0.97–1.76) | 0.07 | 1.27 (0.89–1.81) | 0.18 |
55+ | 61 | 2.66 (1.82–3.90) | <.01 | 2.67 (1.69–4.21) | <.01 |
Sex1 | 0.039 | ||||
Male | 504 | 1.00 | |||
Female | 332 | 0.76 (0.58–0.99) | |||
Karnofsky score at autoHCT | 0.011 | 0.011 | |||
≥90 | 575 | 1.00 | 1.00 | ||
<90 | 240 | 1.49 (1.14–1.94) | <.01 | 1.49 (1.09–2.04) | 0.01 |
Missing | 21 | 1.55 (0.72–3.35) | 0.26 | 2.36 (1.02–5.45) | 0.05 |
Number of lines of chemotherapy | <.001 | Not significant | |||
1 | 95 | 1.00 | |||
2 | 462 | 0.91 (0.60–1.39) | 0.66 | ||
3 | 196 | 1.23 (0.78–1.94) | 0.37 | ||
4+ | 65 | 1.71 (1.01–2.87) | 0.04 | ||
Missing | 18 | 2.87 (1.44–5.70) | <.01 | ||
TBI as part of conditioning | <.001 | <.001 | |||
No | 797 | 1.00 | 1.00 | ||
Yes | 39 | 2.65 (1.73–4.05) | <.001 | 2.62 (1.54–4.45) | <.001 |