Table 1.

The Effects of VOEE on PTZ-Induced Convulsion in Mice.^a

Treatment (Dose)	Onset (s)	Duration (s)	Seizure Protection (%)	Mortality Protection (%)
Normal saline (10 mL/kg)	57.2 ± 9.45	19.20 ± 0.8	0	0
Diazepam (1 mg/kg)	405.6 ± 35.9**	6 ± 0.45***	100	100
VOEE (100 mg/kg)	95.8 ± 15.42	17 ± 1.63	16	33
VOEE (200 mg/kg)	257.2 ± 102.4	14.8 ± 0.97*	33	67
VOEE (400 mg/kg)	333 ± 77.40*	10.4 ± 0.25***	83	100

Abbreviations: PTZ, pentylenetetrazole; VOEE, Verbena officinalis ethanol extract.

^aNormal saline, diazepam, and VOEE were administered 30 minutes before the injection of PTZ (90 mg/kg, intraperitoneally). Values are mean ± standard error of the mean for 6 mice.

*P < .05, **P < .01, ***P < .001 compared with the saline group.