Table 4.
Antifungal Activity of Essential Oil of Salvia mirzayanii against Azole-Sensitive and Azole-Resistant Candida.
| Species (Number) | MIC50, GM µL/mL (Range) | MIC95, GM µL/mL (Range) | MFC, GM µL/mL (Range) | |
|---|---|---|---|---|
| Azole sensitive | C albicans (16) | 0.54 (0.25-1) | 1.29 (0.5-2) | 3.66 (2-8) |
| C ubliniensis (2) | 0.06 (0.03-0.12) | 0.17 (0.06-0.5) | 1 (0.5-2) | |
| C glabrata (5) | 0.16 (0.03-0.5) | 0.32 (0.06-1) | 2.63 (1-2) | |
| C krusei (1) | 0.25 | 1 | 4 | |
| C parapsilosis (6) | 0.31 (0.12-0.5) | 0.79 (0.25-1) | 3.56 (1-8) | |
| C tropicalis (1) | 0.12 | 0.25 | 1 | |
| Azole resistant | C albicans (6) | 0.49 (0.12-1) | 1.78 (1-2) | 4.48 (4-8) |
| C tropicalis (2) | 0.7 (0.5-1) | 2 | 4 | |
Abbreviations: GM, geometric mean; MIC, minimum inhibitory concentration; MFC, minimum fungicidal concentration.