Figure 4. Apoptosis assay with stably (A-498) or transient (Caki-1) transfected empty and DKK4 renal cancer cells and protein expression of apoptosis markers.
A. Flow cytometry analysis of apoptosis in empty vector and stable DKK4 clone 1 and clone 2 cells and transient DKK4 transfectants of Caki-1 cells. Annexin V-FITC and 7-AAD were measured by flow cytometry. Representative results are also shown (B). Data are the mean ± S.D. of four independent experiments. C. Protein expression of pro-caspase-3 and cleaved caspase3 in empty and DKK4 stable transfectants (A-498) and DKK4 transient transfectants (Caki-1).