Table 3.
Cox multivariate analysis of the risk factors for primary cutaneous melanoma metastasis of 244 patients seen at the services of dermatology and surgical oncology (1995-2012)
| Variable | Hazard Ratio* | CI 95% | P value |
|---|---|---|---|
| Gender | |||
| Male | Reference** | ||
| Female | 0.46 | 0.24-0.90 | 0.0222 |
| Clinicopathological type | |||
| Superficial spreading and lentigo maligna melanoma | Reference | ||
| Nodular | 2.89 | 1.19-7.03 | 0.0196 |
| Acral | 1.50 | 0.48-4.72 | 0.4857 |
| Breslow thickness | |||
| ≤1mm | Reference | ||
| 1,01 to 4mm | 3.00 | 0.94-9.57 | 0.0628 |
| >4mm | 7.85 | 2.27-27.16 | 0.0011 |
| Ulceration | |||
| No | Reference | ||
| Yes | 2.14 | 1.04-4.40 | 0.0391 |
CI: Confidence interval;
*
Risk of metastasis as calculated by the Cox method.
**
exp(-coef): 2.1509