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. Author manuscript; available in PMC: 2018 Apr 10.
Published in final edited form as: Leukemia. 2017 Oct 10;32(4):865–873. doi: 10.1038/leu.2017.307

Figure 2.

Figure 2

DNMT1 positively regulates VEGF and FABP4 expression. (a and b) C1498, MV4-11 or Kasumi-1 cells were transfected with DNMT1 siRNA and subjected to Western blotting (a) or qPCR (b). (c) Western blotting in MV4-11 or Kasumi-1 cells treated with 2 µM decitabine for 72 hours. (d) 293T or Kasumi-1 cells were transfected with DNMT1 expression vectors and subjected to Western blotting. (e and f) Spearman correlation analysis for the mRNA expression of FABP4 and DNMT3a or DNMT3b in AML patients (GSE12417; GPL570, e; GPL96, f). The Y or X-axis represents the fold change in maximum expression. For Western blotting and qPCR, the experiments were performed 3 times independently; Data are shown as mean values ± SD, *P < 0.05, **P < 0.01.