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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Curr Opin Genet Dev. 2017 Nov 10;48:57–66. doi: 10.1016/j.gde.2017.10.008

Figure 1.

Figure 1

Diagram of the major pre-mRNA splicing pathway. Subunits with recurrent acquired mutations in cancers are colored cyan. BPS, branchpoint sequence; ESE, exonic splicing enhancer; ILC, intron-lariat complex.