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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Curr Opin Genet Dev. 2017 Nov 10;48:57–66. doi: 10.1016/j.gde.2017.10.008

Figure 2.

Figure 2

SRSF2 (cyan) has recurrent acquired mutations in CMML and MDS. The hotspot P95 residue (yellow) is here shown mapped on the protein (a) domains and (b) structure (PDB ID 2LEB), which includes residues 1–101 and is bound to RNA sequence 5′-UCCAGU-3′ (magenta).