Table 3.
Levels of Variation in Intraocular Pressure and the Four-year Risk of Developing Open-angle Glaucoma Stratified by Mean Intraocular Pressure
| IOP <15 mmHg |
IOP ≥15 mmHg |
|||||||
|---|---|---|---|---|---|---|---|---|
| N | Incidence rate | OR (95% CI)a | Pa | N | Incidence rate | OR (95% CI)a | Pa | |
| SD of IOP | ||||||||
| ≤1 mmHg | 832 | 1.0% | 1.00 (reference) | - | 493 | 2.6% | 1.00 (reference) | - |
| >1, ≤2 mmHg | 974 | 1.8% | 1.77 (0.75–4.19) | 0.19 | 592 | 1.2% | 0.35 (0.12–0.97) | 0.043 |
| >2, ≤3 mmHg | 309 | 1.9% | 2.10 (0.71–6.23) | 0.18 | 242 | 2.5% | 0.96 (0.34–2.68) | 0.93 |
| >3 mmHg | 96 | 6.3% | 5.85 (1.81–18.92) | 0.003 | 128 | 7.8% | 1.80 (0.67–4.82) | 0.24 |
| Range of IOP | ||||||||
| ≤2 mmHg | 841 | 1.1% | 1.00 (reference) | - | 514 | 2.7% | 1.00 (reference) | - |
| >2, ≤4 mmHg | 928 | 1.7% | 1.62 (0.70–3.74) | 0.26 | 538 | 1.3% | 0.38 (0.14–1.04) | 0.061 |
| >4, ≤6 mmHg | 344 | 1.7% | 1.66 (0.57–4.80) | 0.35 | 276 | 2.2% | 0.86 (0.31–2.36) | 0.76 |
| >6 mmHg | 98 | 6.1% | 5.37 (1.70–16.97) | 0.004 | 127 | 7.1% | 1.50 (0.55–4.11) | 0.43 |
Abbreviations: CI=confidence interval; IOP=intraocular pressure; OR=odds ratio; SD=standard deviation.
a
Estimated from logistic regression models adjusting for baseline variables including age, axial length, lack of vision insurance, waist to hip ratio, central corneal thickness, and mean IOP.