Table 2.

Associations between Residential Proximity to Major Roadway and Outcomes

Outcome	Exposure	Model 1*		Model 2†		Model 3‡
		HR	95% CI	HR	95% CI	HR	95% CI
Ischemic Stroke	<100 m	1.08	0.80, 1.45	1.35	0.96, 1.91	1.42	1.01, 2.02
	100– <200 m	0.92	0.69, 1.24	1.16	0.83, 1.61	1.14	0.81, 1.60
	200– <400 m	1.00	0.77, 1.31	1.10	0.83, 1.48	1.08	0.80, 1.45
	≥400 m	---	---	---	---	---	---
	Log(distance)§	1.04	0.93, 1.15	1.11	1.01, 1.23	1.13	1.02, 1.25
Myocardial Infarction	<100 m	1.15	0.85, 1.56	1.01	0.71, 1.45	1.00	0.69, 1.44
	100– <200 m	1.03	0.77, 1.37	0.89	0.63, 1.27	0.89	0.63, 1.26
	200– <400 m	1.08	0.82, 1.40	1.09	0.81, 1.47	0.98	0.72, 1.33
	≥400 m	---	---	---	---	---	---
	Log(distance)§	1.05	0.95, 1.16	1.00	0.89, 1.12	1.00	0.89, 1.14
All-cause Mortality	<100 m	0.85	0.74, 0.98	0.95	0.81, 1.12	0.95	0.81, 1.13
	100– <200 m	0.92	0.81, 1.04	1.06	0.91, 1.23	1.04	0.90, 1.21
	200– <400 m	0.90	0.80, 1.01	1.07	0.94, 1.21	1.04	0.91, 1.18
	≥400 m	---	---	---	---	---	---
	Log(distance)§	0.95	0.91, 1.00	0.99	0.94, 1.04	1.00	0.95, 1.06
Vascular Mortality	<100 m	0.86	0.70, 1.07	0.92	0.72, 1.17	0.92	0.71, 1.19
	100– <200 m	0.90	0.74, 1.09	0.92	0.78, 1.23	0.94	0.74, 1.19
	200– <400 m	0.90	0.76, 1.08	1.04	0.85, 1.26	1.00	0.82, 1.23
	≥400 m	---	---	---	---	---	---
	Log(distance)§	0.94	0.87, 1.02	0.97	0.90, 1.05	0.98	0.89, 1.07

HR:hazard ratio, CI:Confidence interval. Scaled to interquartile range change

^*unadjusted model

^†adjusted for age at baseline, sex, race-ethnicity, education, insurance status, year of baseline, neighborhood socioeconomic status

^‡adjusted for variables in Model 2 plus smoking, alcohol use, physical activity, body mass index, hypertension, high density lipoprotein levels, diabetes, any cardiac disease