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. 2017 Sep 19;70(4):223–236. doi: 10.1007/s00251-017-1028-0

Table 5.

Functionality comparison of non-reference V alleles to their reference allele. Novel V alleles were defined as F, ORF, or P and this was compared to the original allele. The type of change is represented in the Change column, and the relative proportions of each are in the Fraction column

Class Change Fraction Sum
Loss F->ORF 4.61% 23.78%
F->P 14.29%
ORF->P 4.89%
Gain ORF->F 0.70% 3.37%
P->F 1.20%
P->ORF 1.48%
None PP 13.69% 72.85%
FF 50.50%
OO 8.66%