Table 2.
The odds ratio estimate with 95% credible intervals of AEs for each pair-wise comparison.
| ADA+MTX | 0.84 (0.38, 1.8) | 1.20 (0.41, 3.56) | 0.40 (0.10, 1.51) | 0.79 (0.20, 3.16) | 0.66 (0.21, 2.03) | 1.17 (0.37, 3.63) | 1.09 (0.39, 2.86) | 0.97 (0.19, 4.26) | 0.91 (0.29, 2.39) | 1.40 (0.52, 3.74) |
| 1.19 (0.55, 2.61) | cDMARDs | 1.42 (0.68, 3.06) | 0.47 (0.16, 1.42) | 0.95 (0.30, 2.97) | 0.78 (0.34, 1.84) | 1.40 (0.60, 3.19) | 1.30 (0.69, 2.34) | 1.15 (0.28, 4.10) | 1.08 (0.49, 2.05) | 1.67 (0.90, 3.06) |
| 0.84 (0.28, 2.46) | 0.70 (0.33, 1.48) | CZP+MTX | 0.33 (0.09, 1.26) | 0.66 (0.17, 2.59) | 0.55 (0.18, 1.70) | 0.98 (0.31, 2.94) | 0.91 (0.34, 2.34) | 0.81 (0.16, 3.53) | 0.76 (0.25, 1.99) | 1.16 (0.44, 3.06) |
| 2.51 (0.66, 9.78) | 2.12 (0.70, 6.30) | 3.00 (0.79, 11.7) | ETN | 2.01 (0.41, 9.78) | 1.65 (0.42, 6.49) | 2.97 (0.75, 11.82) | 2.75 (0.76, 9.49) | 2.44 (0.40, 13.07) | 2.29 (0.58, 8.00) | 3.53 (1.00, 12.43) |
| 1.26 (0.32, 5.05) | 1.05 (0.34, 3.32) | 1.51 (0.39, 5.93) | 0.50 (0.1, 2.41) | ETN+MTX | 0.83 (0.20, 3.39) | 1.48 (0.36, 6.05) | 1.38 (0.37, 4.90) | 1.22 (0.20, 6.62) | 1.14 (0.28, 4.10) | 1.75 (0.49, 6.49) |
| 1.52 (0.49, 4.85) | 1.28 (0.54, 2.97) | 1.82 (0.59, 5.70) | 0.61 (0.15, 2.39) | 1.21 (0.30, 5.00) | GOL | 1.79 (0.78, 4.10) | 1.67 (0.57, 4.57) | 1.48 (0.28, 6.69) | 1.39 (0.43, 3.82) | 2.12 (0.76, 5.99) |
| 0.85 (0.28, 2.72) | 0.71 (0.31, 1.67) | 1.02 (0.34, 3.19) | 0.34 (0.08, 1.34) | 0.68 (0.17, 2.80) | 0.56 (0.24, 1.28) | GOL+MTX | 0.93 (0.32, 2.59) | 0.83 (0.16, 3.78) | 0.78 (0.24, 2.16) | 1.19 (0.43, 3.39) |
| 0.91 (0.35, 2.56) | 0.77 (0.43, 1.45) | 1.09 (0.43, 2.97) | 0.36 (0.11, 1.31) | 0.73 (0.20, 2.72) | 0.60 (0.22, 1.77) | 1.07 (0.39, 3.10) | IFX+MTX | 0.89 (0.19, 3.67) | 0.84 (0.31, 2.01) | 1.27 (0.55, 3.13) |
| 1.03 (0.23, 5.26) | 0.87 (0.24, 3.6) | 1.23 (0.28, 6.30) | 0.41 (0.08, 2.51) | 0.82 (0.15, 5.10) | 0.68 (0.15, 3.53) | 1.21 (0.26, 6.36) | 1.13 (0.27, 5.21) | PBO | 0.93 (0.30, 2.92) | 1.43 (0.41, 5.99) |
| 1.09 (0.42, 3.46) | 0.92 (0.49, 2.03) | 1.31 (0.50, 4.06) | 0.44 (0.12, 1.73) | 0.88 (0.24, 3.56) | 0.72 (0.26, 2.34) | 1.28 (0.46, 4.18) | 1.20 (0.50, 3.22) | 1.07 (0.34, 3.32) | TCZ | 1.52 (0.82, 3.39) |
| 0.71 (0.27, 1.93) | 0.60 (0.33, 1.11) | 0.86 (0.33, 2.27) | 0.28 (0.08, 1.00) | 0.57 (0.15, 2.05) | 0.47 (0.17, 1.31) | 0.84 (0.3, 2.34) | 0.79 (0.32, 1.8) | 0.70 (0.17, 2.46) | 0.66 (0.30, 1.22) | TCZ+MTX |
cDMARDs, conventional disease-modifying antirheumatic drugs; MTX, methotrexate; ADA, adalimumab; CZP, certolizumab; ETN, etanercept; GOL, golimumab; IFX, infliximab; TCZ, tocilizumab; PBO, placebo.