Table 3.
ADA+MTX | 1.00 (0.64, 1.55) | 1.05 (0.52, 2.16) | 0.96 (0.40, 2.27) | 0.42 (0.15, 1.19) | 0.92 (0.36, 2.29) | 1.16 (0.55, 2.32) | 1.13 (0.59, 2.18) | 1.11 (0.61, 2.01) |
1.00 (0.64, 1.55) | cDMARDs | 1.05 (0.60, 1.86) | 0.95 (0.45, 2.01) | 0.42 (0.16, 1.07) | 0.91 (0.41, 2.05) | 1.16 (0.63, 1.99) | 1.12 (0.71, 1.80) | 1.11 (0.73, 1.65) |
0.95 (0.46, 1.93) | 0.95 (0.54, 1.67) | CZP+MTX | 0.90 (0.35, 2.27) | 0.40 (0.13, 1.20) | 0.87 (0.33, 2.32) | 1.09 (0.48, 2.36) | 1.06 (0.52, 2.23) | 1.04 (0.52, 2.10) |
1.04 (0.44, 2.48) | 1.05 (0.50, 2.20) | 1.11 (0.44, 2.83) | ETN+MTX | 0.44 (0.13, 1.43) | 0.96 (0.32, 2.83) | 1.23 (0.46, 3.03) | 1.19 (0.50, 2.86) | 1.16 (0.49, 2.69) |
2.36 (0.84, 6.82) | 2.36 (0.93, 6.17) | 2.51 (0.84, 7.61) | 2.25 (0.70, 7.61) | GOL | 2.16 (0.90, 5.64) | 2.75 (0.92, 8.25) | 2.66 (0.96, 7.61) | 2.61 (0.94, 7.39) |
1.08 (0.44, 2.75) | 1.09 (0.49, 2.46) | 1.15 (0.43, 3.06) | 1.04 (0.35, 3.10) | 0.46 (0.18, 1.12) | GOL+MTX | 1.27 (0.46, 3.35) | 1.21 (0.48, 3.16) | 1.20 (0.49, 2.97) |
0.86 (0.43, 1.80) | 0.86 (0.50, 1.58) | 0.91 (0.42, 2.10) | 0.81 (0.33, 2.18) | 0.36 (0.12, 1.08) | 0.79 (0.30, 2.16) | IFX+MTX | 0.96 (0.48, 2.12) | 0.95 (0.49, 1.95) |
0.89 (0.46, 1.68) | 0.90 (0.55, 1.40) | 0.94 (0.45, 1.93) | 0.84 (0.35, 1.99) | 0.38 (0.13, 1.04) | 0.83 (0.32, 2.08) | 1.04 (0.47, 2.08) | TCZ | 0.98 (0.61, 1.52) |
0.90 (0.50, 1.65) | 0.90 (0.61, 1.36) | 0.96 (0.48, 1.93) | 0.86 (0.37, 2.03) | 0.38 (0.14, 1.06) | 0.84 (0.34, 2.03) | 1.05 (0.51, 2.05) | 1.02 (0.66, 1.63) | TCZ+MTX |
cDMARDs, conventional disease-modifying antirheumatic drugs; MTX, methotrexate; ADA, adalimumab; CZP, certolizumab; ETN, etanercept; GOL, golimumab; IFX, infliximab; TCZ, tocilizumab; PBO, placebo.