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. 2018 Mar 21;12:183. doi: 10.3389/fnins.2018.00183

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Copyright © 2018 Martinon and Dabrowska.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CRFR2 blockade increases OT content in BNST_dl microdialysates. OT content in BNST_dl microdialysates is expressed as MEAN ± SEM of OT (pg) in 100 μl microdialysis samples for ACSF (A) and As2B (B) treated groups. Baseline samples were collected in 30 min intervals before a drug delivery. (A) Perfusion of ACSF alone did not affect OT content in BNST_dl microdialysates. (B) There was a significant main treatment effect in rats perfused with As2B (one-way ANOVA), and post-hoc analysis showed significantly increased OT content in the first sample collected after drug infusion (30 min, ^*P < 0.05) in comparison to pre-treatment OT content (Bonferroni's multiple comparisons).