Figure 3.

Manipulation of CRFR2 affects OT content in BNST_dl microdialysates. OT content in the microdialysates collected at 30 min intervals is expressed as percent change from the baseline. Data is expressed as mean ± SEM. Although CRFR2 activation by Ucn3 did not significantly affect OT release (n = 7, olive, closed square), an increase in OT release at 30 and 90 min was induced by intra-BNST_dl application of the CRFR2 antagonist, As2B (n = 14, purple, closed circle) in comparison to vehicle (ACSF) group (n = 19, black, closed triangle, P < 0.01). ^**P < 0.01, ^*P < 0.05, two-way ANOVA with repeated measures; Bonferroni's multiple comparisons test.