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. 2018 Mar 21;12:183. doi: 10.3389/fnins.2018.00183

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Copyright © 2018 Martinon and Dabrowska.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of CRFR2 antagonist (As2B) on OT content in BNST_dl microdialysates is modulated by CRFR1 manipulation. The effect of As2B on OT release at 30 min was occluded by intra-BNST_dl application of CRFR1 antagonist NBI 35965 (n = 6, teal, open circle, P < 0.05) as well as application of CRF (n = 7, blue diamond, P < 0.01). The delayed stimulatory effect of As2B at 90 min was not affected by CRF or NBI 35965 application (P > 0.05). ^**P < 0.01, ^*P < 0.05, two-way ANOVA with repeated measures.