Table 3.
Patients with secondary appearance of COL7 Ab at relapse (N = 10) | Patients without secondary appearance COL7 Ab at relapse (N = 14) | P value | |
---|---|---|---|
Mean age ± SD (range), years | 79.8 ± 14.3 (45–95) | 81.4 ± 9.6 (57.95) | 1.00 |
Sex ratio (female/male) | 2.5 | 1.3 | 0.52 |
Total BPDAI (mean ± SD) | 57.3 ± 34.0 | 52.3 ± 17.0 | 0.72 |
Skin BPDAI (mean ± SD) | 54.2 ± 32.4 | 51.5 ± 16.7 | 1.00 |
Mucosal involvement, no. (%) | 6 (60.0) | 5 (35.7) | 0.24 |
The clinical characteristics at baseline of BP patients who further relapsed under treatment were analyzed according to the secondary appearance of anti-type VII collagen autoantibodies at relapse (COL7 Ab).
BPDAI, Bullous Pemphigoid Disease Area Index; BP, bullous pemphigoid.