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. 2018 Mar 28;24(12):1361–1372. doi: 10.3748/wjg.v24.i12.1361

Table 3.

SVR12 in cirrhotic and non-cirrhotic hepatitis C virus genotype 1b-infected patients with and without resistance-associated polymorphisms at baseline (immediate treatment arm) n (%)

Patients with cirrhosis - immediate treatment arm
With RAPs at baseline
Without RAPs at baseline
Mainland China Russia South Korea Overall Mainland China Russia South Korea Overall
Patients with cirrhosis
NS5A-L31M/V 0 0 0 0 15/16 (93.8) 0 2/3 (66.7) 17/19 (89.5)
Y93H 0 0 0 0 15/16 (93.8) 0 2/3 (66.7) 17/19 (89.5)
L31M/V or Y93H 0 0 0 0 15/16 (93.8) 0 2/3 (66.7) 17/19 (89.5)
NS3-D168E 0 0 0 0 15/16 (93.8) 0 2/3 (66.7) 17/19 (89.5)
Patients without cirrhosis
NS5A-L31M/V 1/1 (100) 1/1 (100) 0 2/2 (100) 93/101 (92.1) 21/22 (95.5) 8/10 (80.0) 122/133 (91.7)
Y93H 7/13 (53.8) 0 0/2 (0) 7/15 (46.7) 87/89 (97.8) 22/23 (95.7) 8/8 (100) 117/120 (97.5)
L31M/V or Y93H 8/14 (57.1) 1/1 (100) 0/2 (0) 9/17 (52.9) 86/88 (97.7) 21/22 (95.5) 8/8 (100) 115/118 (97.5)
NS3-D168E 0/1 (0) 0 0 0/1 (0) 94/101 (93.1) 22/23 (95.7) 8/10 (80.0) 124/134 (92.5)

RAP: Resistance-associated polymorphism; SVR12: Sustained virologic response at posttreatment week 12.