Table 4.
SVR12 in hepatitis C virus genotype 1b-infected patients with and without resistance-associated polymorphisms at baseline (placebo-deferred treatment arm) n (%)
All patients - placebo-deferred treatment arm |
|||||||||
With RAPs at baseline |
Without RAPs at baseline |
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Mainland China | Russia | South Korea | Overall | Mainland China | Russia | South Korea | Overall | ||
NS5A-L31M/V | 0 | 0 | 0 | 0 | 33/41 (80.5) | 6/6 (100) | 3/3 (100) | 42/50 (84.0) | |
Y93H | 2/8 (25.0) | 0 | 0 | 2/8 (25.0) | 31/33 (93.9) | 6/6 (100) | 3/3 (100) | 40/42 (95.2) | |
L31M/V or Y93H | 2/8 (25.0) | 0 | 0 | 2/8 (25.0) | 31/33 (93.9) | 6/6 (100) | 3/3 (100) | 40/42 (95.2) | |
NS3-D168E | 0 | 0 | 0 | 0 | 33/41 (80.5) | 6/6 (100) | 3/3 (100) | 42/50 (84.0) |
RAP: Resistance-associated polymorphism; SVR12: Sustained virologic response at posttreatment week 12.