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. Author manuscript; available in PMC: 2018 Mar 28.
Published in final edited form as: J Med Chem. 2017 Aug 18;60(17):7244–7255. doi: 10.1021/acs.jmedchem.7b00228

Figure 3.

Figure 3

Compound 38u specifically inhibits AEP. (A) Structures of compound 38 and its derivatives with increased hydrophobicity. (B) IC50 curves for compound 38 and its derivatives against pure AEP. (C) Inhibition specificity assay. IC50 values of compound 38 and its derivatives against AEP and other related major cysteine proteases.