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. Author manuscript; available in PMC: 2018 Mar 28.
Published in final edited form as: J Med Chem. 2017 Aug 18;60(17):7244–7255. doi: 10.1021/acs.jmedchem.7b00228

Figure 4.

Figure 4

Compound 38u inhibits invasion in vitro. (A) Effect of compound 38u on cell proliferation, invasion, and migration of MDA-MB-231 cells. Cell proliferation was determined by MTT assay, following incubation with the compound. (B) Effect of compound 38u on cell proliferation, invasion, and migration of MDA-MB-435 cells. Cell proliferation was determined by MTT assay, following incubation with the compound. (C) Effect of compound 38u on AEP activity in MDA-MB-231 and MDA-MB-435 cells. AEP activity were examined with lysate of cells treated by 38u (D) Effect of compound 38u on invasion of MDA-MB-231 and MDA-MB-435 cells treated by control and AEP siRNA.