Skip to main content
. Author manuscript; available in PMC: 2018 Mar 28.
Published in final edited form as: J Med Chem. 2017 Aug 18;60(17):7244–7255. doi: 10.1021/acs.jmedchem.7b00228

Figure 6.

Figure 6

Compound 38u does not exhibit toxic effects in mice. (A) IHC sections of bone marrow, kidney, liver, and spleen from animals treated with vehicle control or 3 or 10 mg/kg of compound 38u show similar results in vehicle and drug-treated tissues. (B) There was no significant difference in body weight observed in mice treated with vehicle control or compound 38u. (C) The size of the liver remained similar in vehicle and drug-treated animals, however, the spleen was slightly enlarged in drug-treated animals as compared to control.