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Phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mTOR pathway adapted from figure 2 of [6] and figure 1 of [16]. Insulin receptor substrate (IRS), phosphatase and tensin homolog (PTEN), phosphatidylinositol bisphosphate (PIP2), phosphatidylinositol trisphosphate (PIP3), tuberous sclerosis (TSC), Ras homolog enriched in brain (Rheb), S6 kinase beta-1 (S6K1).
