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. 2018 Jan 9;8(1):6. doi: 10.3390/bios8010006

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Electrochemical inhibition assay for buspirone. (A) Nyquist plots drawn for various buspirone concentrations (0.1, 0.2, 0.4, 0.8, 1.0 μM). (B) Calibration curve of EC biosensor for indirect buspirone detection based on normalized R_ct values. Each value represents mean and standard deviation of five measurements. (C) Nyquist plots drawn for control studies performed with Etoposide and APAP at the same concentration of buspirone (1.0 μM). (D) Bar graphs with mean and SD (n = 5) for signal comparison between control drugs and buspirone at the same concentration (1.0 μM).