Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Assignment of likely CYP2C19 phenotypes based on genotypes. Adapted from [68], used with permission of John Wiley and Sons; copyright 2013.
| Phenotype | Example Genotypes | Enzyme Activity |
|---|---|---|
| Ultra-rapid metabolizer (UM) | *1/*17 | Normal or increased |
| *17/*17 | ||
| Extensive metabolizer (EM) | *1/*1 (wild type) | Normal |
| Intermediate metabolizer (IM) | *1/*2 | Intermediate |
| *1/*3 | ||
| *2/*17 | Likely intermediate | |
| *3/17 | Likely intermediate | |
| Poor metabolizer (PM) | *2/*2 | Low or absent |
| *3/*3 | ||
| *2/*3 |
