Table 3.
Comparison of gene polymorphisms between family control and cancer groups.
| Genes | Control (n = 54) |
Cancer (n = 54) |
p-Value | |
|---|---|---|---|---|
| MTHFR 677 | 0 (CC) 1 (CT) 2 (TT) |
28 (51.9%) 21 (38.9%) 5 (9.3%) |
23 (42.6%) 25 (46.3%) 6 (11.1%) |
0.6285 |
| MTHFR 1298 | 0 (AA) 1 (AC) 2 (CC) |
32 (59.2%) 15 (27.8%) 7 (13.0%) |
34 (63.0%) 15 (27.8%) 5 (9.2%) |
0.8212 |
| MTR 2756 | 0 (AA) 1 (AG) 2 (GG) |
39 (72.2%) 12 (22.2%) 3 (5.6%) |
36 (66.7%) 17 (31.5%) 1 (1.8%) |
0.3712 |
| MTRR 66 | 0 (AA) 1 (AG) 2 (GG) |
28 (52.4%) 18 (33.6%) 7 (13.0%) |
19 (35.6%) 25 (46.8%) 10 (18.5%) |
0.1842 |
| DHFR 19 bp | Del/Del Ins/Del Ins/Ins |
20 (37.0%) 17 (31.5%) 17 (31.5%) |
13 (24.1%) 25 (46.3%) 16 (29.6%) |
0.2188 |
| Total Polymorphism (0–10) | ≥4 mean ± SD (range) |
16 (29.6%) 3.1 ± 1.3 (0–6) |
27 (50.0%) 3.3 ± 1.4 (1–5) |
0.0306 0.0819 |
The statistically significant values have been highlighted in red. Ins: Insertion; Del: Deletion.