Table 1.
Top genome-wide association hits at p < 1.0 × 10−6.
| Genes | #SNPs | CHR | SNP ID | Position | Minor Allele | Reference Allele | MAF Cases | MAF Controls | OR | p-Value |
|---|---|---|---|---|---|---|---|---|---|---|
| (intronic) CACNB4 | rs150793926 | 152781063 | GTA | G | 0.04 | 0.07 | 0.49 | 4.10 × 10−8 | ||
| 8 | 2 | rs113760736 | 152800750 | C | T | 0.03 | 0.07 | 0.50 | 1.50 × 10−7 | |
| rs12623883 | 152790117 | A | G | 0.03 | 0.06 | 0.50 | 2.45 × 10−7 | |||
| (intronic) MGAM | 1 | 7 | rs4341082 | 141759846 | T | C | 0.38 | 0.47 | 0.70 | 4.50 × 10−7 |
| (intergenic) THSD7A, THEM106B | 1 | 7 | rs74676849 | 11889492 | G | A | 0.1 | 0.05 | 2.03 | 6.80 × 10−7 |
SNPs: single nucleotide polymorphisms or short indels; CHR: chromosome; OR: odds ratio.