Table 1.
Physicochemical properties of Pluronic® PEO-PPO-PEO block copolymers often used in drug formulation. Data obtained from [40]. cmc, critical micellization concentration; L, liquid; P, paste; F, flake.
| Pluronic® Notation | MW | PO Units | EO Units | cmc at 25 °C (% w/v) | cmc at 30 °C (% w/v) | cmc at 35 °C (% w/v) |
|---|---|---|---|---|---|---|
| L64 | 2900 | 30 | 26 | n/a | 1.5 | 0.4 |
| P65 | 3400 | 17 | 36 | n/a | 4 | 1 |
| P84 | 4200 | 43 | 38 | 2.6 | 0.6 | 0.15 |
| P85 | 4600 | 40 | 52 | 4 | 0.9 | 0.2 |
| F88 | 11,400 | 39 | 206 | n/a | n/a | 1.7 |
| P103 | 4950 | 60 | 34 | 0.07 | 0.01 | 0.002 |
| P104 | 5900 | 61 | 54 | 0.3 | 0.04 | 0.008 |
| P105 | 6500 | 56 | 74 | 0.3 | 0.025 | 0.005 |
| F108 | 14,600 | 50 | 264 | 4.5 | 0.8 | 0.15 |
| P123 | 5750 | 69 | 38 | 0.03 | 0.005 | 0.001 |
| F127 | 12,600 | 65 | 200 | 0.7 | 0.1 | 0.025 |