Table 7.
Biomaterials used for polyjet printing.
Materials | Process | Test Model | Key Findings | Ref. |
---|---|---|---|---|
Elastic photopolymer (FullCure 930 TangoPlus) by Stratasys | 3D printed live size aortic aneurysum phantom from patients CT files using a Stratasys Eden 260 polyjet printer. The phantom cost was $254.49 and took 13 hours to 3D print. | Mock surgical procedure was performed under live fluoroscope using the 3D printed phantom | Pre-surgical planning & simulation was possible with patient-specific abdominal aortic aneurysm phantom. Simulation was effective in planning surgical challenges & complications than standard procedures (2D image diagnostics). | [45] |
Rigid acrylic resin (AR-M2) for Agilista-3200 3D printer, Japan | 3D printed patient-specific intrahepatic vessel models | Preoperative planning in hepatocellular carcinoma resection procedure | The use of 3D printed intrahepatic vessel models from patient’s data (CT files) has greatly improved the surgical quality of the hepatocellular carcinoma procedure. | [46] |
Photopolymer resin | 3D printed customized surgical aids (cutting and repositioning guides) for genioplasty. CAD/CAM models were created from the patients CT images and patient specific surgical guides were fabricated using SLA based 3D printer (3D systems). | Genioplasty performed on 88 patients with dentofacial deformities | 3D printed genioplasty templates provided greater accuracy in the surgical procedures than traditional intraoperative measurements. | [47] |
Multiple photopolymer resins on Connex 3 polyjet | Printed at 16 µm layer height | 3D printed anatomical phantoms of liver and microspheres from patient’s CT data | These phantoms offered a method to quantify radiation dose form Y-90 microspheres for treatment of liver cancer | [48] |
Multiple photopolymer resins printed using Connex 350 | Printed anatomical liver with different materials for vasculature and biliary structures | Used as preoperative surgical guidance model for 3 cases of liver transplant | 6 patient specific liver models were 3D printed (3 living donor and 3 recipients). Significantly improved surgery and minimized intraoperative complications. | [49] |
Multiple photopolymer resins printed using Objet 500 Connex | Printed anatomical model of head with different materials for skin, bone and tissues | Used these models as a training tool for neuro surgery | Significantly improved the training experience of surgeons by improving navigation and planning | [50] |
Photopolymer RGD525 and Connex 500 | Printed with polymers that are visible under MRI scanners | Spine model containing C6–C8 vertebrae including tumors in them. | Anatomically accurate phantoms that can be imaged under CT and MRI were developed. Improving preoperative planning for MR guided minimally invasive surgeries. | [51] |
Multiple photopolymers and Objet 350 Connex | Materials with different rigidity were used to mimic native tissue’s mechanical properties. | Different models such as hollow aneurysm, craniocerebral aneurysm, and craniocerebral tumors | Aneurysm clippings and tumor resection planning were efficiently planned with these models | [52] |
Multiple photopolymers and Objet studio | Materials with different flexibilities were used | 50 patients were randomly chosen to explain medical procedure using 3D printed model | 3D printed model of nasal sinus anatomy was used as educational tool to enable patients to make informed decision. Results suggest improved patient comfort levels and outcomes. | [53] |
Projet 3512 HD | Rigid material was used to create molds for nephrology sectioning. | 5 patient specific slicing guides were 3D printed for partial nephrectomy | Enabled accurate sectioning of tumors for colocalization analysis for radiomic and radiogenomic analyses | [54] |