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. 2018 Feb 13;7(1):12. doi: 10.3390/antibiotics7010012

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The northern-derived (NDR) and southern-derived (SDR) clades are closely related sister-taxa and yet were isolated from soils of different latitude. The un-rooted tree was constructed from multiple whole genome alignments with maximum likelihood and a GTRGAMMA model of evolution. Scale bar represents nucleotide substitutions per site. Colored branches depict the northern-derived (NDR) and southern-derived (SDR) clades. Strain names reflect the sample site they were isolated from (Table S1). Genome NBRC 13350 is the publically available type strain Streptomyces griseus subsp. griseus NBRC 13350. Sample locations are shown in the right panel and labeled with the site code. Circles are colored to reflect the geographic distribution of clades. (Figure modified from [29]).