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Accumulation and efflux of ethidium bromide of the M. tuberculosis strains. (A) Accumulation of ethidium bromide in the presence of efflux inhibitors. In these cases, the strains were loaded with 0.25 µg/mL of ethidium bromide in the presence of verapamil or thioridazine at ½ MIC; (B) Efflux of ethidium bromide. Strains were loaded with ethidium bromide at 0.25 µg/mL; efflux took place in the presence of glucose which was inhibited by verapamil at ½ MIC.
