TABLE 1.
Summary of Parameters Used in the Track Structure Model of Changes to Dendritic Morphology
Parameter | Symbol | Units |
---|---|---|
Mean particle fluence | F | Number per μm2 |
Linear energy transfer | LET | keV/μm |
Absorbed dose | DF | Gy |
Impact parameter (radial distance from particle to dendritic segment or soma) | b | Microns (μm) |
Radial dose | D(b) | Gy |
Dendritic segment diameter | dCyl | Microns (μm) |
Dendritic segment volume | Vcyl | Cubic microns (μm3) |
Frequency mean specific energy in dendrite cylindrical segment | zF(b, dCyl) | Gy |
Absorbed dose corresponding to reduction in dendritic length by one-half | DHV | Gy |
Damage response-sensitivity parameters | ||
Sensitivity parameter for soma apoptosis | DTH,S | Gy |
Sensitivity parameter for dendrite snip | DTH,D | Gy |
Sensitivity for neuron death due to dendritic length reduction | DL | Unitless |
Note. Other model parameters specifically related to random damage models are described in the discussion of Eqs. (7–9).