Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan 19;6(1):8. doi: 10.3390/medsci6010008

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Impact of lysine decarboxylase on polyamine synthesis. Genes encoding the enzymes Lys9, NspC, AguB and AguA that catalyze reactions in the polyamine biosynthesis pathways are arranged as a single operon in the genome, and Transcription of this operon is downregulated in ΔcadA. Reactions that involve multiple steps are represented by a broken arrow. We identified reduced expression of lys9, nspC, aguA and speE in ΔcadA compared to TIGR4 by qRT-PCR. Expression of Lys9 and NspC proteins were reduced in lysine decarboxylase impaired pneumococci.