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Effect of 20 mg/kg Compound 6 on body weight using two dosing regimens. (a) Body weight loss in grams following dosing once or twice, 6 h apart, for four consecutive days. (b) Percent body weight loss following dosing once or twice, 6 h apart, for four consecutive days. Two groups of 8-week old Female Swiss CD.1 mice were injected SC with 20 mg/kg of Compound 6 (n = 8). Mice were weighed daily for 7 days. Each point indicates mean ± SEM.
