Table 2.

Results of binary logistic regression analysis with 3- and 12-month weight loss as dependent variable (<5% weight loss is reference) and the genotypes as independent variables

Gene	rs number	Genotype/model	OR (95% CI)	p value1	OR2 (95% CI)	p value1, 2
3 months
PLIN1	rs2289487	C/C vs. T/T-T/C3	1.92 (1.17–3.13)	0.009	1.94 (1.18–3.18)	0.009
PLIN1	rs2304795	G/G vs. A/A-G/A3	1.75 (1.10–2.79)	0.018	1.75 (1.09–2.80)	0.020
PLIN1	rs1052700	T/T vs. A/A-T/A3	1.72 (1.04–2.82)	0.033	1.74 (1.05–2.88)	0.031
MMP2	rs1132896	C/C vs. G/G-G/C3	1.83 (1.13–2.96)	0.014	1.84 (1.13–2.99)	0.014
12 months
PPARγ	rs1801282	C/C vs. C/G-G/G4	2.03 (1.07–3.87)	0.025	2.25 (1.17–4.34)	0.012
TIMP4	rs3755724	T/C vs. C/C-T/T5	2.03 (1.21–3.41)	<0.001	2.03 (1.19–3.45)	0.008

OR, odds ratio; 95% CI, 95% confidence interval.

¹p value not corrected for multiple SNPs.

²Adjusted for BMI and age as covariates.

³Recessive.

⁴Dominant.

⁵Overdominant.