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Incidence of grade ≥ 3 adverse events
| Grade ≥ 3 adverse events | Afatinib (%) | Pemetrexed-cisplatin (%) |
|---|---|---|
| Neutropenia | 0.4 | 18.0 |
| Fatigue | 1.3 | 12.6 |
| Anaemia | 0.4 | 6.3 |
| Nausea | 0.9 | 3.6 |
| Diarrhoea | 14.4 | 0.0 |
| Rash | 16.2 | 0.0 |
| Vomiting | 3.1 | 2.7 |
Source: Sequist et al, [6]
