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. 2018 Mar 13;2018:7859601. doi: 10.1155/2018/7859601

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Copyright © 2018 Yao Wang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(a–c) Effect of CAY10683 on small intestine damages in ALF rats: (a) normal group, (b) model group, and (c) CAY10683 group. (d) Effect of CAY10683 on the intestinal permeability in ALF rats. (e) Effect of CAY10683 on the mRNA expression of TLR4, ZO-1, and occludin in ALF rats. (f) Effect of CAY10683 on HDAC2 and acetyl-H3 in ALF rats. (g) Effect of CAY10683 on the protein levels of ZO-1, occludin, TLR4, MyD88, TRIF, and TRAF6 protein levels in ALF rats. Values are expressed as mean ± SD. ^#P < 0.05, compared with normal group; ^∗P < 0.05, compared with model group.