Table 9.

The selected predicted regulation of dysregulated lncRNAs on mRNAs in COPD patients compared to smokers.

lncRNA	Gene symbol	Target gene	Microarray analyze fold change	Function
NR_026891.1	FLJ10038	CXCL16	2.29	Induced by the inflammatory cytokines IFN-gamma and TNF-alpha; cytokine-cytokine receptor interaction, organism-specific biosystem
ENST00000502883.1	RP11-499E18.1	CXCL16	2.29	Induced by the inflammatory cytokines IFN-gamma and TNF-alpha; cytokine-cytokine receptor interaction, organism-specific biosystem
HIT000648516	—	HMOX1	2.71	Keap1-Nrf2 pathway, organism-specific biosystem
XR_429541.1	—	SLA2	0.46	Negative regulation of B cell activation; regulation of immune response TCR signaling in naive CD4+ T cells
ENST00000597550.1	CTD-2245F17.3	SIGLEC14	2.57	Innate immune system Cell adhesion