Table 2.
Histological evaluation of liver of mice treated with fermented Cucurbita moschata extract.
| Groups | Steatosis | Ballooning | Portal inflammation | Lobular activity | Fatty changes (lipidosis) |
|---|---|---|---|---|---|
| ND | 0.67 ± 0.58d | 0.00 ± 0.00d | 0.00 ± 0.00b | 0.00 ± 0.00c | 0.33 ± 0.58b |
| HFD | 4.67 ± 0.58a | 4.00 ± 1.00a | 3.33 ± 1.15a | 2.67 ± 1.53a | 5.00 ± 0.00a |
| HFD + 0.3% HCA | 2.00 ± 0.00bc | 2.00 ± 1.00b | 1.00 ± 1.00b | 1.33 ± 0.58abc | 0.67 ± 0.58b |
| HFD + 0.1% FCME | 2.67 ± 0.58b | 1.67 ± 0.58bc | 1.00 ± 1.00b | 1.67 ± 0.58ab | 1.00 ± 1.00b |
| HFD + 0.3% FCME | 1.00 ± 1.00cd | 0.67 ± 0.58cd | 0.33 ± 0.58b | 0.67 ± 0.58bc | 0.33 ± 0.58b |
| HFD + 0.5% FCME | 0.33 ± 0.58d | 0.00 ± 0.00d | 0.67 ± 0.58b | 0.00 ± 0.00bc | 0.67 ± 0.58b |
Duncan's multiple range test. 0: absent; 1: few; 2: mild; 3: moderate; 4: severe; and 5: extremely severe. ND: normal diet; HFD: high fat diet; HCA: hydroxycitric acid; FCME: fermented Cucurbita moschata extract; values not having the same superscript letter are significantly different (p < 0.05) by ANOVA.